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Lewy body dementia

Print

Overview

Lewy body dementia, also known as dementia with Lewy bodies, is the second most common type of progressive dementia after Alzheimer's disease dementia. Protein deposits, called Lewy bodies, develop in nerve cells in the brain regions involved in thinking, memory and movement (motor control).

Lewy body dementia causes a progressive decline in mental abilities. People with Lewy body dementia may experience visual hallucinations, and changes in alertness and attention. Other effects include Parkinson's disease-like symptoms such as rigid muscles, slow movement and tremors.

Lewy body dementia care at Mayo Clinic

Symptoms

Lewy body dementia signs and symptoms may include:

  • Visual hallucinations. Hallucinations may be one of the first symptoms, and they often recur. They may include seeing shapes, animals or people that aren't there. Sound (auditory), smell (olfactory) or touch (tactile) hallucinations are possible.
  • Movement disorders. Signs of Parkinson's disease (parkinsonian symptoms), such as slowed movement, rigid muscles, tremor or a shuffling walk may occur.
  • Poor regulation of body functions (autonomic nervous system). Blood pressure, pulse, sweating and the digestive process are regulated by a part of the nervous system that is often affected by Lewy body dementia. This can result in dizziness, falls and bowel issues such as constipation.
  • Cognitive problems. You may experience thinking (cognitive) problems similar to those of Alzheimer's disease, such as confusion, poor attention, visual-spatial problems and memory loss.
  • Sleep difficulties. You may have rapid eye movement (REM) sleep behavior disorder, which can cause you to physically act out your dreams while you're asleep.
  • Fluctuating attention. Episodes of drowsiness, long periods of staring into space, long naps during the day or disorganized speech are possible.
  • Depression. You may experience depression sometime during the course of your illness.
  • Apathy. You may have loss of motivation.
Request an Appointment at Mayo Clinic

Causes

Lewy body dementia is characterized by the abnormal buildup of proteins into deposits known as Lewy bodies. This protein is also associated with Parkinson's disease. People who have Lewy bodies in their brains often have the plaques and tangles associated with Alzheimer's disease.

Risk factors

A few factors seem to increase the risk of developing Lewy body dementia, including:

  • Being older than 60
  • Being male
  • Having a family member with Lewy body dementia or Parkinson's disease

Research has indicated that depression is also associated with Lewy body dementia.

Complications

Lewy body dementia is progressive. Signs and symptoms worsen, causing:

  • Severe dementia
  • Aggressive behavior
  • Depression
  • Increased risk of falling and injury
  • Worsening of parkinsonian symptoms, such as tremors
  • Death, on average about eight years after symptoms start
By Mayo Clinic Staff

Lewy body dementia care at Mayo Clinic

Request an Appointment at Mayo Clinic
Diagnosis & treatment
Aug. 09, 2017
Print
References
  1. NINDS Dementia with Lewy bodies information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/dementiawithlewybodies/dementiawithlewybodies.htm. Accessed Feb. 16, 2016.
  2. Hake AM, et al. Clinical features and diagnosis of dementia with Lewy bodies. http://www.uptodate.com/home. Accessed Feb. 16, 2016.
  3. Hake AM, et al. Epidemiology, pathology, and pathogenesis of dementia with Lewy bodies. http://www.uptodate.com/home. Accessed Feb. 16, 2016.
  4. Diagnosis. Lewy Body Dementia Association. http://www.lbda.org/content/diagnosis. Accessed Feb. 16, 2016.
  5. Hake AM, et al. Prognosis and treatment of dementia with Lewy bodies. http://www.uptodate.com/home. Accessed Feb. 16, 2016.
  6. Symptoms. Lewy Body Dementia Association. http://www.lbda.org/content/symptoms. Accessed Feb. 16, 2016.
  7. Neurological diagnostic tests and procedures. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/misc/diagnostic_tests.htm. Accessed Feb. 16, 2016.
  8. Shadlen MF, et al. Evaluation of cognitive impairment and dementia. http://www.uptodate.com/home. Accessed Feb. 16, 2016.
  9. Dementia: Hope through research. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/dementias/detail_dementia.htm. Accessed Feb. 16, 2016.
  10. Communication and Alzheimer's. Alzheimer's Association. http://www.alz.org/care/dementia-communication-tips.asp. Accessed Feb. 16, 2016.
  11. Creating a daily plan. Alzheimer's Association. http://www.alz.org/care/dementia-creating-a-plan.asp. Accessed Feb. 16, 2016.
  12. Press D. Treatment of dementia. http://www.uptodate.com/home. Accessed Feb. 16, 2016.
  13. Sleep issues and sundowning. Alzheimer's Association. http://www.alz.org/care/alzheimers-dementia-sleep-issues-sundowning.asp. Accessed Feb. 16, 2016.
  14. Buettner LL, et al. Animal-assisted therapy for clients with dementia. Journal of Gerontological Nursing. 2011;37:10.
  15. Being a healthy caregiver. Alzheimer's Association. http://www.alz.org/care/alzheimers-dementia-healthy-caregiver.asp. Accessed Feb. 16, 2016.
  16. Respite care. Alzheimer's Association. http://www.alz.org/care/alzheimers-dementia-caregiver-respite.asp. Accessed Feb. 16, 2016.
  17. Caregiver stress. Alzheimer's Association. http://www.alz.org/care/alzheimers-dementia-caregiver-stress-burnout.asp. Accessed Feb. 16, 2016.
  18. Dementia with Lewy bodies. Alzheimer's Association. http://www.alz.org/dementia/dementia-with-lewy-bodies-symptoms.asp. Accessed Feb. 16, 2016.
  19. Home safety and Alzheimer's. Alzheimer's Association. https://www.alz.org/care/alzheimers-dementia-home-safety.asp. Accessed Feb. 16, 2016.
  20. Stay mentally active. Alzheimer's Association. https://www.alz.org/care/alzheimers-dementia-home-safety.asp. Accessed Feb. 18, 2016.
  21. Press D, et al. Management of neuropsychiatric symptoms of dementia. http://www.uptodate.com/home. Accessed Feb. 18, 2016.
  22. Therapeutic activities. Fisher Center for Alzheimer's Research Foundation. https://www.alzinfo.org/articles/therapeutic-activities/. Accessed Feb. 18, 2016.
  23. Boot BP, et al. Risk factors for dementia with Lewy bodies. Neurology. 2013; 81: 833.
  24. Graff-Radford J (expert opinion). Mayo Clinic, Rochester, Minn. Feb. 22, 2016.

Mayo Clinic has been recognized as the best Neurology & Neurosurgery hospital in the nation for 2017-2018.

Mayo Clinic in Rochester, Minnesota, ranks No. 1 for neurology and neurosurgery in the U.S. News & World Report Best Hospitals rankings. Mayo Clinic in Scottsdale, Arizona, and Mayo Clinic in Jacksonville, Florida, are ranked among the Best Hospitals for neurology and neurosurgery by U.S. News & World Report. Mayo Clinic also ranks among the Best Children's Hospitals for neurology and neurosurgery.

Learn more about this top honor

Lewy body dementia

  • Symptoms & causes
  • Diagnosis & treatment
  • Doctors & departments
  • Care at Mayo Clinic
CON-20166450


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Christian louboutin in pelle highness piattaforma peep toe pompe viola bianco 160mm Christian louboutin in vernice a punta Pompe mimosa 120mm 2016, christian louboutin lady peep picchi pompe della pelle verniciata 150mm d'oro 2016 christian louboutin australia 2018 christian louboutin une plume vernice cunei framboise 140mm 2016 Christian louboutin 20 anni signora gres pompe camoscio caldo 160mm rosa Christian louboutin Daf Booty 160mm Tartan Ankle Stivali Blu 2016 Christian louboutin Daffodile 160mm Paris Rose Suede 2017 Christian louboutin nuovo declic pitone Pompe Roccia 120mm 2016.

piattaforme christian louboutin 2018 Christian louboutin Daffodile pelle nera pompe di 160mm 2017 9,7/10(da 33018 voti) 110,25 EUR fornitori:
su:christian louboutin lady peep picchi pompe della pelle verniciata 150mm d'oro 2016 / prossimo:christian louboutin no. Prive tessuto chanel scintillava multicolor 120mm 2017

Index

 

christian louboutin nuove arachidi zeppe in pelle nera 45mm 2016, Christian louboutin Daffodile strass piattaforma pompe nero 160mm 2016 kpROhO

 

 
 

 

 

 

 

 

 

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